2005 Ford E-350 fuel system problems

The contact owned a 2005 Ford E-350. The contact stated while driving approximately 45 MPH he smelled a burning odor and saw that the vehicle was trailing a large white cloud. The contact stated no warning light was illuminated. The contact pulled over and as soon as he exited the vehicle it had become engulfed in flames. The contact stated that the flames came from under the rear of the vehicle.

While drive on highway,vehicle began to lose power when I encountered a hill. It bogged down and struggled to make it to top of hill and lost speed down to 30 MPH or less and then died. It would not start right away, but after letting it sit for 15 minutes, it started and had regained power and I drove it till I got to the nest hill and did the same thing several times till I made it home 3 hours later for a 10 mile trip.