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2006 Isuzu I-280 fuel economy

The EPA lists 2 versions of the 2006 Isuzu I-280. Combined fuel economy ranges from 17 to 21 MPG; the most efficient version is rated 18 city / 25 highway.

At a glance

Combined
17 to 21 MPG depending on version
City and highway
18 and 25 most efficient version
Yearly fuel cost
$3,200 EPA estimate, most efficient version

Source: U.S. EPA fueleconomy.gov

Every version the EPA tested

VersionEngineDriveCityHighwayCombinedYearly fuel cost
i-280 Extended Cab 2WD
Manual 5-spd
4-cyl 2.8L Rear-Wheel Drive 182521 MPG $3,200
i-280 Extended Cab 2WD
Automatic 4-spd
4-cyl 2.8L Rear-Wheel Drive 152217 MPG $3,950
EPA estimates under standard test conditions. Your mileage will vary with driving style, load and weather.

At EPA assumptions, the most efficient version costs about $3,200 per year in fuel, versus $3,950 for the least efficient.

Work out what this car would cost you in fuel each year

Fuel economy in other model years