2021 Lexus ES250
The EPA rates the 2021 Lexus ES250 at 28 MPG combined (25 city / 34 highway).
At a glance
- Fuel economy
- 28 MPG combined
Sources: NHTSA complaints, recalls and 5-Star ratings; U.S. EPA
Fuel economy
The EPA rates the 2021 Lexus ES250 at 28 MPG combined (25 city / 34 highway).