2021 Lexus ES350
The EPA rates the 2021 Lexus ES350 at 26 MPG combined (22 city / 32 highway).
At a glance
- Fuel economy
- 26 MPG combined
Sources: NHTSA complaints, recalls and 5-Star ratings; U.S. EPA
Fuel economy
The EPA rates the 2021 Lexus ES350 at 26 MPG combined (22 city / 32 highway).