2026 Lexus IS 350
The EPA lists 2 versions of the 2026 Lexus IS 350. Combined fuel economy ranges from 22 to 22 MPG; the most efficient version is rated 19 city / 27 highway.
At a glance
- Fuel economy
- 22 MPG combined
Sources: NHTSA complaints, recalls and 5-Star ratings; U.S. EPA
Fuel economy
The EPA lists 2 versions of the 2026 Lexus IS 350. Combined fuel economy ranges from 22 to 22 MPG; the most efficient version is rated 19 city / 27 highway.