2025 Lexus LS500
The EPA lists 2 versions of the 2025 Lexus LS500. Combined fuel economy ranges from 21 to 22 MPG; the most efficient version is rated 18 city / 29 highway.
At a glance
- Fuel economy
- 21 to 22 MPG combined
Sources: NHTSA complaints, recalls and 5-Star ratings; U.S. EPA
Fuel economy
The EPA lists 2 versions of the 2025 Lexus LS500. Combined fuel economy ranges from 21 to 22 MPG; the most efficient version is rated 18 city / 29 highway.