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2021 Mercedes-Benz AMG E53 fuel economy

The EPA lists 3 versions of the 2021 Mercedes-Benz AMG E53. Combined fuel economy ranges from 23 to 25 MPG; the most efficient version is rated 22 city / 29 highway.

At a glance

Combined
23 to 25 MPG depending on version
City and highway
22 and 29 most efficient version
Yearly fuel cost
$3,300 EPA estimate, most efficient version

Source: U.S. EPA fueleconomy.gov

Every version the EPA tested

VersionEngineDriveCityHighwayCombinedYearly fuel cost
AMG E53 4matic Plus
Automatic 9-spd
6-cyl 3.0L Hybrid 4-Wheel Drive 222925 MPG $3,300
AMG E53 4matic Plus Coupe
Automatic 9-spd
6-cyl 3.0L Hybrid 4-Wheel Drive 212824 MPG $3,400
AMG E53 4matic Plus Convertible
Automatic 9-spd
6-cyl 3.0L Hybrid 4-Wheel Drive 212723 MPG $3,550
EPA estimates under standard test conditions. Your mileage will vary with driving style, load and weather.

At EPA assumptions, the most efficient version costs about $3,300 per year in fuel, versus $3,550 for the least efficient.

Work out what this car would cost you in fuel each year

Fuel economy in other model years