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2020 Mercedes-Benz CLS 450 fuel economy

The EPA rates the 2020 Mercedes-Benz CLS 450 at 26 MPG combined (24 city / 31 highway).

At a glance

Combined
26 MPG
City and highway
24 and 31 most efficient version
Yearly fuel cost
$3,150 EPA estimate, most efficient version

Source: U.S. EPA fueleconomy.gov

Every version the EPA tested

VersionEngineDriveCityHighwayCombinedYearly fuel cost
CLS450
Automatic 9-spd
6-cyl 3.0L Hybrid Rear-Wheel Drive 243126 MPG $3,150
EPA estimates under standard test conditions. Your mileage will vary with driving style, load and weather.

At EPA assumptions, the most efficient version costs about $3,150 per year in fuel.

Work out what this car would cost you in fuel each year

Fuel economy in other model years