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2016 Mercedes-Benz CLS400 fuel economy

The EPA lists 2 versions of the 2016 Mercedes-Benz CLS400. Combined fuel economy ranges from 22 to 24 MPG; the most efficient version is rated 20 city / 30 highway.

At a glance

Combined
22 to 24 MPG depending on version
City and highway
20 and 30 most efficient version
Yearly fuel cost
$3,400 EPA estimate, most efficient version

Source: U.S. EPA fueleconomy.gov

Every version the EPA tested

VersionEngineDriveCityHighwayCombinedYearly fuel cost
CLS400
Automatic 7-spd
6-cyl 3.0L Rear-Wheel Drive 203024 MPG $3,400
CLS400 4matic
Automatic 7-spd
6-cyl 3.0L 4-Wheel Drive 192622 MPG $3,750
EPA estimates under standard test conditions. Your mileage will vary with driving style, load and weather.

At EPA assumptions, the most efficient version costs about $3,400 per year in fuel, versus $3,750 for the least efficient.

Work out what this car would cost you in fuel each year

Fuel economy in other model years