2015 Mercedes-Benz E 400 4MATIC
The EPA rates the 2015 Mercedes-Benz E 400 4MATIC at 22 MPG combined (20 city / 27 highway).
At a glance
- Fuel economy
- 22 MPG combined
Sources: NHTSA complaints, recalls and 5-Star ratings; U.S. EPA
Fuel economy
The EPA rates the 2015 Mercedes-Benz E 400 4MATIC at 22 MPG combined (20 city / 27 highway).