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2023 Mercedes-Benz E 450 4MATIC Coupe fuel economy

The EPA rates the 2023 Mercedes-Benz E 450 4MATIC Coupe at 24 MPG combined (21 city / 30 highway).

At a glance

Combined
24 MPG
City and highway
21 and 30 most efficient version
Yearly fuel cost
$3,400 EPA estimate, most efficient version

Source: U.S. EPA fueleconomy.gov

Every version the EPA tested

VersionEngineDriveCityHighwayCombinedYearly fuel cost
E450 4matic Coupe
Automatic 9-spd
6-cyl 3.0L Hybrid All-Wheel Drive 213024 MPG $3,400
EPA estimates under standard test conditions. Your mileage will vary with driving style, load and weather.

At EPA assumptions, the most efficient version costs about $3,400 per year in fuel.

Work out what this car would cost you in fuel each year

Fuel economy in other model years