2025 Toyota Sienna fuel economy
The EPA lists 2 versions of the 2025 Toyota Sienna. Combined fuel economy ranges from 35 to 36 MPG; the most efficient version is rated 36 city / 36 highway.
At a glance
- Combined
- 35 to 36 MPG depending on version
- City and highway
- 36 and 36 most efficient version
- Yearly fuel cost
- $1,850 EPA estimate, most efficient version
Source: U.S. EPA fueleconomy.gov
Every version the EPA tested
| Version | Engine | Drive | City | Highway | Combined | Yearly fuel cost |
|---|---|---|---|---|---|---|
| Sienna 2WD Automatic (AV-S6) | 4-cyl 2.5L Hybrid | Front-Wheel Drive | 36 | 36 | 36 MPG | $1,850 |
| Sienna AWD Automatic (AV-S6) | 4-cyl 2.5L Hybrid | All-Wheel Drive | 34 | 36 | 35 MPG | $1,900 |
At EPA assumptions, the most efficient version costs about $1,850 per year in fuel, versus $1,900 for the least efficient.