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2013 Mercedes-Benz E 350 4MATIC fuel economy

The EPA lists 6 versions of the 2013 Mercedes-Benz E 350 4MATIC. Combined fuel economy ranges from 22 to 22 MPG; the most efficient version is rated 19 city / 28 highway.

At a glance

Combined
22 MPG
City and highway
19 and 28 most efficient version
Yearly fuel cost
$3,750 EPA estimate, most efficient version

Source: U.S. EPA fueleconomy.gov

Every version the EPA tested

VersionEngineDriveCityHighwayCombinedYearly fuel cost
E350 4Matic
Automatic 7-spd
6-cyl 3.5L FFV 4-Wheel Drive 192822 MPG $3,750
E350 4matic
Automatic 7-spd
6-cyl 3.5L 4-Wheel Drive 192822 MPG $3,750
E350 4matic (wagon)
Automatic 7-spd
6-cyl 3.5L 4-Wheel Drive 192722 MPG $3,750
E350 4matic Coupe
Automatic 7-spd
6-cyl 3.5L 4-Wheel Drive 192922 MPG $3,750
E350 4matic Coupe
Automatic 7-spd
6-cyl 3.5L FFV 4-Wheel Drive 192722 MPG $3,750
E350 4matic Coupe
Automatic 7-spd
6-cyl 3.5L 4-Wheel Drive 192722 MPG $3,750
EPA estimates under standard test conditions. Your mileage will vary with driving style, load and weather.

At EPA assumptions, the most efficient version costs about $3,750 per year in fuel.

Work out what this car would cost you in fuel each year

Fuel economy in other model years