2006 Mercedes-Benz E350 fuel economy
The EPA lists 2 versions of the 2006 Mercedes-Benz E350. Combined fuel economy ranges from 19 to 20 MPG; the most efficient version is rated 17 city / 25 highway.
At a glance
- Combined
- 19 to 20 MPG depending on version
- City and highway
- 17 and 25 most efficient version
- Yearly fuel cost
- $4,100 EPA estimate, most efficient version
Source: U.S. EPA fueleconomy.gov
Every version the EPA tested
| Version | Engine | Drive | City | Highway | Combined | Yearly fuel cost |
|---|---|---|---|---|---|---|
| E350 Automatic 7-spd | 6-cyl 3.5L | Rear-Wheel Drive | 17 | 25 | 20 MPG | $4,100 |
| E350 (wagon) Automatic 7-spd | 6-cyl 3.5L | Rear-Wheel Drive | 16 | 24 | 19 MPG | $4,350 |
At EPA assumptions, the most efficient version costs about $4,100 per year in fuel, versus $4,350 for the least efficient.