2020 Mercedes-Benz E 350 4MATIC
The EPA rates the 2020 Mercedes-Benz E 350 4MATIC at 25 MPG combined (22 city / 30 highway).
At a glance
- Fuel economy
- 25 MPG combined
Sources: NHTSA complaints, recalls and 5-Star ratings; U.S. EPA
Fuel economy
The EPA rates the 2020 Mercedes-Benz E 350 4MATIC at 25 MPG combined (22 city / 30 highway).