2027 Mercedes-Benz E 350 4MATIC
The EPA rates the 2027 Mercedes-Benz E 350 4MATIC at 27 MPG combined (24 city / 33 highway).
At a glance
- Fuel economy
- 27 MPG combined
Sources: NHTSA complaints, recalls and 5-Star ratings; U.S. EPA
Fuel economy
The EPA rates the 2027 Mercedes-Benz E 350 4MATIC at 27 MPG combined (24 city / 33 highway).